PROGAST Butyrate Complex

PROGAST Butyrate: Gut-Brain Axis and Cellular Support for Digestive Health, Immunity and Mental Clarity

Advanced delayed-release formula for microbiome balance, inflammation control and metabolic function

PROGAST Butyrate is a clean, scientifically formulated supplement that offers targeted support for both the gut and the brain. Featuring a specialised blend of butyric acid (as sodium 3-hydroxybutyrate), L-glutamine, calcium, zinc, magnesium, and copper, this formula provides multi-level support for intestinal integrity, cognitive function and metabolic resilience. Designed for delayed release to deliver active compounds directly to the lower digestive tract, it reflects The Good Stuff’s holistic approach to nutritional care and functional wellbeing.

Protects and repairs the intestinal lining

Butyric acid is a short-chain fatty acid naturally produced by gut bacteria and plays a critical role in maintaining the integrity of the gut lining. PROGAST Butyrate delivers this vital compound in a bioavailable form, helping to reduce inflammation, reinforce the intestinal barrier, and support repair of damaged tissues. L-glutamine further enhances gut lining repair by acting as a fuel source for intestinal cells, making this formula particularly supportive for those with leaky gut, IBD symptoms, or post-antibiotic recovery.

Promotes a healthy gut microbiome and nutrient absorption

A thriving microbiome is central to digestion, immune function and long-term wellness. Butyrate not only supports the growth of beneficial bacteria but also helps regulate pH in the colon and improve overall microbial balance. Combined with essential minerals like zinc and magnesium, PROGAST Butyrate encourages better absorption of nutrients, reduces bloating, and supports overall digestive comfort.

Supports the gut-brain axis and cognitive clarity

The gut-brain connection is now widely recognised, and butyrate is a key player in that communication pathway. By reducing neuroinflammation and improving cellular signalling, it may help enhance mood, mental clarity, and memory. Magnesium and zinc further support neurological health, while copper plays a role in energy production and neurotransmitter regulation. PROGAST Butyrate is ideal for those experiencing brain fog, low mood, or cognitive fatigue related to gut dysfunction.

Reduces inflammation and supports immune regulation

Chronic low-grade inflammation in the gut can contribute to a wide range of health issues—from digestive distress to poor immune response and hormonal imbalances. Butyrate helps modulate inflammatory pathways, reducing pro-inflammatory cytokines and supporting a more balanced immune state. This makes the supplement particularly beneficial for individuals managing autoimmune concerns, inflammatory bowel issues, or stress-related immune suppression.

Boosts metabolic health and cellular energy

By supporting mitochondrial function and encouraging efficient cellular repair, PROGAST Butyrate contributes to stronger metabolic performance. Butyric acid has been shown to enhance insulin sensitivity and improve energy metabolism at the cellular level. This makes it a valuable addition to protocols for fatigue, metabolic resistance, and recovery from chronic stress.

Delayed-release delivery for targeted action

The unique delayed-release formulation ensures that the active ingredients bypass the stomach and reach the colon intact—where butyrate is most effective. This targeted delivery increases bioavailability and minimises digestive irritation, offering a more potent and reliable effect than standard formulations.

Clean, well-tolerated and practitioner approved

PROGAST Butyrate is free from unnecessary fillers, synthetic additives and common allergens. Its thoughtful formulation provides everything the gut-brain axis needs—without overcomplicating or overwhelming sensitive systems. It’s suitable for daily use and is a trusted tool in functional gut and cognitive support programmes recommended by The Good Stuff’s team.

Expertly selected by The Good Stuff team

PROGAST Butyrate is one of our most advanced gut-brain support products—perfect for those looking to go deeper with their digestive healing, energy support, and mental clarity. When your gut calms, your thinking sharpens, and your energy returns, we know the body is healing at a foundational level—and that’s the progress we’re here to support.